Module 5: Crisis Intervention and Safety — Final Exam

The MOST dangerous side effect of TCA overdose is:

The anticholinergic side effects of TCAs include which of the following?

Amitriptyline (Elavil) is a TCA that is also commonly used for:

MAOIs (Monoamine Oxidase Inhibitors) work by:

The MOST serious dietary restriction for patients taking MAOIs is the avoidance of:

A hypertensive crisis caused by MAOI and tyramine interaction presents with:

Serotonin Syndrome can occur when MAOIs are combined with:

MAOIs are generally reserved for treatment-resistant depression because:

Phenelzine (Nardil) and tranylcypromine (Parnate) are examples of:

First-generation (typical) antipsychotics (FGAs) work primarily by:

Second-generation (atypical) antipsychotics (SGAs) differ from FGAs primarily because they:

Haloperidol (Haldol) is a high-potency first-generation antipsychotic. Its HIGH POTENCY means it:

Chlorpromazine (Thorazine) is a low-potency first-generation antipsychotic. Its LOW POTENCY means it:

Clozapine (Clozaril) is a second-generation antipsychotic reserved for treatment-resistant schizophrenia. Its MOST dangerous side effect is:

The Absolute Neutrophil Count (ANC) must be monitored in patients taking Clozapine because:

Metabolic syndrome is a significant risk associated with second-generation antipsychotics, particularly Olanzapine (Zyprexa) and Clozapine. Metabolic syndrome includes:

QTc prolongation is a cardiac side effect associated with several antipsychotics (e.g., thioridazine, ziprasidone). It is dangerous because:

Which second-generation antipsychotic is associated with the LEAST weight gain?

Long-acting injectable (LAI) antipsychotics (depot formulations) are used primarily to:

Lithium Carbonate is the gold-standard mood stabilizer for Bipolar Disorder. Its mechanism of action is thought to involve:

The therapeutic serum level for Lithium maintenance therapy is:

Early signs of Lithium toxicity (levels 1.5-2.0 mEq/L) include:

Severe Lithium toxicity (levels > 2.0 mEq/L) can cause:

Valproic Acid (Depakote) is an antiseizure medication also used as a mood stabilizer. Its MOST serious adverse effect is:

Phenytoin (Dilantin) is an antiseizure medication with a well-known side effect of:

Carbamazepine (Tegretol) is an antiseizure medication used as a mood stabilizer. Its MOST serious adverse effects include:

Lamotrigine (Lamictal) is a mood stabilizer particularly effective for the depressive phase of Bipolar Disorder. Its most serious adverse effect is:

Therapeutic drug monitoring (TDM) is particularly important for which medications?

A patient taking Valproic Acid (Depakote) who is of childbearing age should be counseled about:

Extrapyramidal symptoms (EPS) are movement disorders caused primarily by:

Acute Dystonia is an EPS that typically occurs within HOURS TO DAYS of starting an antipsychotic. It is characterized by:

Torticollis is a form of acute dystonia characterized by:

The FIRST-LINE treatment for acute dystonia caused by antipsychotics is:

Akathisia is an EPS characterized by:

Akathisia is MOST commonly treated with:

Pseudoparkinsonism (drug-induced parkinsonism) is an EPS that typically occurs within WEEKS TO MONTHS of antipsychotic therapy. It is characterized by:

Tardive Dyskinesia (TD) is a LATE-ONSET EPS that typically develops after MONTHS TO YEARS of antipsychotic use. It is characterized by:

Tardive Dyskinesia is particularly concerning because:

The EPS timeline from earliest to latest onset is:

Neuroleptic Malignant Syndrome (NMS) is a life-threatening reaction to antipsychotic medications. The classic tetrad of NMS includes:

The MOST important immediate intervention for a patient suspected of having NMS is:

Serotonin Syndrome is caused by excess serotonergic activity in the CNS, most commonly due to:

The classic triad of Serotonin Syndrome includes:

The KEY clinical finding that differentiates Serotonin Syndrome from NMS is:

NMS is associated with HYPOREFLEXIA and ‘lead-pipe’ rigidity, while Serotonin Syndrome is associated with:

The onset of Serotonin Syndrome is typically:

The treatment for Serotonin Syndrome includes:

An SSRI overdose in a patient who is also taking tramadol (an opioid with serotonergic properties) is at HIGH RISK for:

Dantrolene is a muscle relaxant sometimes used in the treatment of NMS. It works by: